Iodo-Nonoxynol-9-Derivatives and Methods for Their Use
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منابع مشابه
Phase I safety & preliminary acceptability of nonoxynol-9 vaginal pessary as a vaginal microbicide in low risk women in Pune, India.
BACKGROUND & OBJECTIVES Though nonoxynol-9 (N-9) is available in India as a spermicidal pessary, data on its safety as a potential microbicide among Indian women are not available. Nonoxynol-9 containing compounds have shown anti-HIV activity in in vitro studies and protection against cervical infections. Nonoxynol-9 is being extensively evaluated as a vaginal microbicide world-wide. We assesse...
متن کاملDo spermicides containing nonoxynol-9 prevent sexually transmitted infections? A meta-analysis.
BACKGROUND AND OBJECTIVES There are conflicting opinions on whether to recommend spermicides containing nonoxynol-9 for prevention of sexually transmitted diseases, including human immunodeficiency virus (HIV). GOAL To systematically review and summarize the medical literature on the effect of spermicides containing nonoxynol-9 on prevention of gonorrhea, chlamydial infection, and HIV. STUD...
متن کاملEffectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial.
BACKGROUND Nonoxynol-9 (rINN, nonoxinol-9) is an over-the-counter spermicide that has in-vitro anti-HIV-1 activity. Results of studies of its effectiveness in prevention of HIV-1 infection in women have been inconclusive. We aimed to assess effectiveness of this vaginal gel. METHODS We did a randomised, placebo-controlled, triple-blinded, phase 2/3 trial with COL-1492, a nonoxynol-9 vaginal g...
متن کاملEffectiveness of Col-1492, a Nonoxynol-9 Vaginal Gel, on Hiv-1 Transmission in Female Sex Workers: a Randomised, Controlled Trial
Van Damme L, Ramjee G, Alary M, et al. Lancet. 2002; 360:962–964 Purpose of the Study. Nonoxynol-9, marketed as a spermicidal contraceptive, has in vitro anti-human immunodeficiency virus (HIV) activity. This study was designed to assess the effectiveness of COL-1492, a nonoxynol-9 vaginal gel, in the prevention of HIV infection in women with a high risk of HIV exposure. Methods. This was a ran...
متن کاملAre there alternatives to nonoxynol-9 spermicide?
You're certainly not alone in your interest of this method. Spermicide is a popular option for birth control because it is easily accessible, simple to use, and provides added lubrication. Results from recent scientific studies for newer alternatives look promising, but more research is still needed. Some of the new ingredients being studied that may be able to function as spermicide (and provi...
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تاریخ انتشار 2017